| 姓名 | 张西亚 | 性别 | 男 | 出生年月 | 1987.04 |
| 民族 | 汉 | 籍贯 | 河南商丘 | 政治面貌 | 党员 |
| 部门 | js6666金沙登录入口-欢迎您 | 职称 | 副教授 | 职务 | 无 |
| 办公地址 | 文化路校区1号楼222研究室 | 办公电话 | 037163558150 | zhangxiya@henau.edu.cn | |
| 教授课程 | 《仪器分析》、《食品免疫学》、《食品安全案例分析》 | ||||
| 研究方向 | 长期从事食品安全免疫分析快速检测方向的研究，擅长小分子化合物半抗原设计与合成、单克隆抗体及多克隆抗体制备、抗原-抗体识别机制、快速检测技术及产品的开发。 | ||||
| 教育经历 |
2013/09-2017/06，中国农业大学，动物医学基础兽医学专业，博士； 2008/09-2011/06，华中农业大学，动物医学基础兽医学专业，硕士； 2004/09年-2008/06，石河子大学，动物科技学院动物医学专业，学士。 |
||||
| 学术社会兼职 | 无 | ||||
| 科研项目 |
1. 国家基金面上项目，32172298，半抗原中苯环间隔臂连接位点制备抗原对抗体灵敏度影响机制研究， 2022/1-2025/12，主持。 2. 国家青年基金项目，31802249，“turn-on”型荧光能量共振转移侧流层析猝灭效率机制研究及体系的构建， 2019/1-2021/12，结项。 3. 河南科技公关项目，均一识别性泰乐菌素/替米考星抗体的分子识别机制及应用研究，2022/1-2023/12，主持。 3. 河南省高等学校重点科研项目，20A550009，样品富集净化与可视化检测一体化新型免疫分析方法研究，2019/12-2021/12，结项。 4. 河南省高等学校大学生创新训练计划项目，201910466023，苯环邻位、间位和对位作为间隔臂连接位点对小分子化合物特异性抗体产生的影响机制研究，2019/5-2021/4，项目指导老师，结项。 5．河南农业大学青年人才项目，30500645，荧光能量共振转移侧流层析体系的构建， 2018/6-2023/5，主持。 6. 河南农业大学拔尖人才项目，30501305，荧光能量共振转移侧流层析体系的构建， 2022/10-2027/9，在研，主持。 |
||||
| 论文论著 |
以第一作者发表SCI论文： 1. Xiya Zhang#, Yuchen Bai#, Qianqian Tang, Minggang Liu, Li Nan, Kai Wen, Xuezhi Yu, Wenbo Yu, Jianzhong Shen, Zhanhui Wang*, Development of epitopephore-based rational hapten design strategy: A combination of theoretical evidence and experimental validation. Journal of Hazardous Material, 2023(445),130615. 2. Zizhe Li#, Jinkui Wang#, Youyi Wang, Qingyue Li, Xiaoyang Chen, Yu Wang, Haining Tian, Yexuan Mao, Lianjun Song, Xianqing Huang, Zhanhui Wang, Xiya Zhang*, Development of a lateral flow immunoassay based on a highly specific monoclonal antibody to detect 4- methylaminoantipyrine. Journal of Agricultural and Food Chemistry, 2023. 65(36):8063-8071 3. Xiya Zhang#, Zizhe Li#, Yexuan Mao, Meng Dang, Xianqing Huang, Zhanhui Wang, Huijuan Yang, Yuchen Bai*, Huahai Zhang*Production of high-affinity monoclonal antibody and development of immunoassay for 3-methyl-quinoxaline-2-carboxylic acid detection in swine muscle and liver. Food Chemistry, 2023 (407), 135175. 4. Yexuan Mao#, Yichao Fan#, Ran Yang, Youyi Wang, Qingyue Li, Meng Dang, Xianqing Huang, Lianjun Song, Pingan Zhang, Miao Song, Liang Liu, Linli Wang, Shun Yu, Qiuyan Zhao*, Xiya Zhang*, A highly sensitive electrochemical sensor derived from peptide amphiphilic inspired self-assembled, ordered gold nanoparticles for determination of 22 β-lactams. Electrochimica Acta, 461 (2023) , 142669. 5. Meng Dang#, Zizhe Li#, Yexuan Mao, Xianqing Huang, Lianjun Song, Wenfeng Li, Ruxiang Ma, Yang Liu, Liye Wang, Xuezhi Yu, Huijuan Yang*, Xiya Zhang*, A highly sensitive lateral fow immunoassay based on a group‑specifc monoclonal antibody and amorphous carbon nanoparticles for detection of sulfonamides in milk. Microchimica Acta, 190 (2023):186. 6. Yexuan Mao#, Meng Dang, Jianwei Zhang, Xianqing Huang, Mingwu Qiao, Lianjun Song, Qiuyan Zhao, Mingyue Ding, Youyi Wang, Zizhe Li, Ke Song, Qingge Shi, Xiya Zhang*, Peptide amphiphile inspired self-assembled, ordered gold nanocomposites for improved sensitivity of electrochemical immunosensor: Applications in determining the total aflatoxin amount in food stuffs. Talanta, 2022, 247:123532. 7. Xiya Zhang#, Mingyue Ding#, Yexuan Mao, Xianqing Huang, Xinhua Xie, Lianjun Song, Mingwu Qiao, Jianwei Zhang, Tianlin Wang, Haihua Zhu, Zizhe Li, Youyi Wang, Meng Dang*, A comparative study of “turn-off” mode and “turn-on” mode lateral flow immunoassay for T-2 toxin detection. Sensors and Actuators B: Chemical, 2022, 359:131545. 8. Liye Wang#, Jiangxiu Niu, Pengyuan Wei, Yilei Feng, Mingyue Ding, Chaojun He, Yongjie Ma, Yaolei Zhu, Jia Li, Lingli Huang*, Xiya Zhang*, Rapid determination of 2,4-diaminopyrimidine residues through sample pretreatment using immunomagnetic bead purification along with HPLC–UV. Food Chemistry, 2021(376), 131835. 9. Xiya Zhang#, Mingyue Ding, Chensi Zhang, Yexuan Mao, Youyi Wang, Peipei Li, Haiyang Jiang, Zhanhui Wang, and Xuezhi Yu*, Development of a New Monoclonal Antibody against Brevetoxins in Oyster Samples Based on the Indirect Competitive Enzyme-Linked Immunosorbent Assay. Foods, 2021, 10, 2398. 10. Zhang Xiya#, Xijie Zhang, Lianjun Song, Xianqing Huang, Yu Li, Mingwu Qiao, Wanjing Liu, Tongtong Zhang, Yuchen Qi, Wuzhou Wang, Xuezhi Yu, Leina Dou, Huijuan Yang, Liye Wang, Yexuan Mao*, Zhanhui Wang. An ultrasensitive, homogeneous fluorescence quenching immunoassay integrating separation and detection of aflatoxin M1 based on magnetic graphene composites, Microchimica Acta, 2021, 188(59). 11. Xiya Zhang#, Fenfen Zhao, Tiejun Mi, Liye Wang, Qian Li, Jiayin Li, Wentao Ma, Wanjing Liu, Jingnan Zuo, Xinyu Chu, Bing Chen, Wenxin Han, Yexuan Mao*. Development of a highly sensitive lateral flow immunoassay based on receptor-antibody-amorphous carbon nanoparticles to detect 22 β-lactams in milk. Sensors and Actuators B: Chemical, 2020, 321:128458. 12. Xiya Zhang#, Qianqian Tang#, Tiejun Mi, Sijun Zhao, Kai Wen, Liuchuan Guo, Jiafei Mi, Suxia Zhang, Weimin Shi, Jianzhong Shen, Yuebin Ke*, Zhanhui Wang*, Dual-wavelength Fluorescence Polarization Immunoassay to Increase Information Content Per Screen: Applications for Simultaneous Detection of Total Aflatoxins and Family Zearalenones in Maize, Food Control, 2018, 87:100-108. 13. Xiya Zhang#, Ying Wang, Tony Velkov, Shusheng Tang, Chongshan Dai*. T-2 Toxin-induced Toxicity in Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen, Mitochondrial Dysfunction and Inhibition of Nrf2/HO-1 Pathway. Food and Chemical Toxicology, 2018, 114: 88–97. 14. Xiya Zhang#, Xuezhi Yu#, Jianyi Wang, Qi Wang, Hui Meng, Zhanhui Wang*. One-step Core/multishell Quantum Dots-Based Fluoroimmunoassay for Screening of Deoxynivalenol in Maize, Food Analytical Methods, 2018, 11:2569-2578. 15. Xuezhi Yu#, Xiya Zhang#, Zhanhui Wang, Haiyang Jiang, Ziquan Lv, Jianzhong Shen, Guoliang Xia, Kai Wen*, Universal Simultaneous Multiplex ELISA of Small Molecules in Milk Based on Dual Luciferases, Analytica Chimica Acta, 2018, 1001:125-133. 16. Xiya Zhang#, Xuezhi Yu#, Kai Wen, Chenglong Li, Ghulam Mujtaba Mari, Haiyang Jiang, Weimin Shi, Jianzhong Shen, Zhaihui Wang. Multiplex Lateral Flow Immunoassays Based on Amorphous Carbon Nanoparticles for Detecting Three Fusantium Mycotoxins in Maize. Journal of Agricultural and Food Chemistry, 2017, 65(36):8063-8071. 17. Xiya Zhang#, Sergei A. Eremin, Kai Wen, Xuezhi Yu, Chenglong Li, Yuebin Ke, Haiyang Jiang, Jianzhong Shen, Zhanhui Wang*. A Fluorescence Polarization Immunoassay Based on New Monoclonal Antibody for the Detection of Family Zearalenones in Maize [J]. Journal of Agricultural and Food Chemistry, 2017, 65(10): 2240-2247. 18. Xiya Zhang#, Meirong Song, Xuezhi Yu, Zhanhui Wang, Yuebin Ke, Haiyang Jiang, Jiancheng Li, Jianzhong Shen, Kai Wen*. Development of a New Group-Specific Monoclonal Antibody with Uniform Affinity for Aflatoxins and a Magnetic Bead-Based Enzymatic Immunoassay [J]. Food Control, 2017, 79: 309-316. 19. Xiya Zhang#, Kai Wen, Zhanhui Wang, Haiyang Jiang, Ross C. Beier, Jianzhong Shen*. An Ultra-Sensitive Monoclonal Antibody-Based Fluorescent Microsphere Immunochromatographic Test Strip Assay for Detecting Aflatoxin M1 in Milk. Food Control, 2016, 60(2): 588-595. 20. Xiya Zhang#, Chao Wu, Kai Wen, Haiyang Jiang, Jianzhong Shen, Suxia Zhang, Zhanhui Wang*. Comparison of Fluorescent Microspheres and Colloidal Gold as Labels in Lateral Flow Immunochromatographic Assays for the Detection of T-2 Toxin. Molecules, 2015, 21(1), 1-9. Xiya Zhang#, Dapeng Peng#, Yuanhu Pan, Yulian Wang, Dongmei Chen, Qi Zhou, Zhenli Liu, Zonghui Yuan*. A Novel Hapten and Monoclonal Antbibody-Based Enzyme-Linked Immunosorbent Assay for 3-Methyl-Quinoxaline-2-Carboxylic Acid in Edible Animal Tissues. Analytical Methods, 2015, 7(16): 6588-6594. |
||||
| 成果奖励 | 无 | ||||
| 学术交流经历 | 经常参加食品安全、兽医药理学与毒理学、抗体大会、真菌毒素等相关研究的国内及国际会议。 | ||||
| 荣誉称号 | 优秀班主任 | ||||
